US President Joe Biden is leaving his COVID-19 isolation after testing negative twice, the White House said.

Biden tested positive on Thursday and was said to have experienced “very mild symptoms’’.

He went into isolation and was given a five-day course of Paxlovid, a Coronavirus treatment medication.

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White House physician Kevin O’Connor said in a letter that the 79-year- old president tested negative on Tuesday night and again on Wednesday morning.

“His symptoms have been steadily improving, and are almost completely resolved,’’ O’Connor wrote.